Changing trends of HIV infection in children with relation to the ongoing PPTCT programme

  • Rayudu Lakshmi Kumari Department of Microbiology, Siddhartha Medical College, Vijayawada, Andhra Pradesh, India
  • Boorgula Sushma Yadav Department of Microbiology, Siddhartha Medical College, Vijayawada, Andhra Pradesh, India

Abstract

Mother to Child transmission of HIV is a major route of new infections in children .By providing Antiretroviral therapy to HIV infected woman during pregnancy, delivery ,breast feeding & continuing the regimen to infants during breast feeding period will significantly prevent transmission from 30-45% to 2-5%.The aim of the study is to ascertain the changing trends with occurrence of HIV infection in children through the PPTCT programme (launched by Director General NACO on 14th September 2012) in prevention of transmission of HIV from HIV infected mother to child. 259 Antenatal Women registered from September 2012 to June 2013 at 105 ICTC centres in Krishna District were studied.All infants born to HIV infected mother were referred to Early Infant Diagnosis (EID) centres for HIV testing through HIV DNA PCR testing at 6 weeks, 6months, 12 months and final confirmatory test at 18 months. Out of 259 Antenatal Women , ARV Prophylaxis was given to 126, ART given to 69, ART PLUS to 15, single dose Nevirapine to10 , 2 were not eligible for treatment , treatment was not initiated for 35 and 2 have missed the treatment. In 2011April-12 March , out of 337 children tested for Dried Blood Spot ,18 were tested positive .In 2012 April-13 March , out of 253 children for Dried Blood spot ,6 were tested positive .Where as in April 2013 –2013 September out of 146 children tested ,5were detected as HIV positive . In 2013 October-2013 June , out of 267 children tested , 1 case was detected as HIV positive .PPTCT programme can be effective if well conducted , thus minimal infectivity rate can be achieved in infants born to HIV infected mother. Keywords: PPTCT, PMTCT, HIV

Author Biographies

Rayudu Lakshmi Kumari, Department of Microbiology, Siddhartha Medical College, Vijayawada, Andhra Pradesh, India
Department of Microbiology, Siddhartha Medical College, Vijayawada, Andhra Pradesh, India
Boorgula Sushma Yadav, Department of Microbiology, Siddhartha Medical College, Vijayawada, Andhra Pradesh, India
Department of Microbiology, Siddhartha Medical College, Vijayawada, Andhra Pradesh, India

References

Joshi U , Kadri A , Bhojiya S. Indian J Sex Transm Dis.2010 Jul; 31 (2):92-8.

Joint United Nations Programme on HIV / AIDS , World Health Organization AIDS epidemic update 2007.

Dandona L , Lakshmi V , Sudha T , Kumar GA , Dandona R. A BMC Med; 2006;4-31.

Dandona L ,Dandona R. Lancet 2007;370:1811-1813.

National AIDS Control Organisation , Ministry of Health & Family Welfare, Government of India HIV sentinel surveillance and HIV estimation , 2006 .2007.

Dandona L , Kumar SG , Ramesh YK , BMC Health Serv Res.2008 Jan 31;8:26.

Indian Institute of Population Sciences Reproduction and Child health district level survey 2002-04.

National AIDS Control Organisation . Minisrty of Health & Family Welfare. 2011-12 Annual Report.

WHO New guidance on prevention of mother-to-child transmission of HIV and infant feeding in the context of HIV.

Joint United National Programme on HIV/AIDS (UNAIDS).Countdown to zero: global plan for elimination of

new HIV infections among children by 2015 and keeping their mothers alive, 2011-2012.Geneva ,UNAIDS,2011.

http://www.unaids.org/en/media/unaids/contentassets/documents/unaidspublication/ 201120110609_JC2137_Global-Plan-Elimination-HIV-Children_en.pdf

WHO.World report on knowledge for better health: strengthening health systems.2004.

Systematic review of public health research on prevention of mother-to-child transmission of HIV in India with focus on provision and utilization of cascade of PMTCT services. Shrinivas Darak, MayuriPanditrao, RituParchure, VinayKulkarni , Sanjeevani Kulkarni and Fanny Janssen

Published
2017-03-26
Section
Article