Changing trends of HIV infection in children with relation to the ongoing PPTCT programme
AbstractMother to Child transmission of HIV is a major route of new infections in children .By providing Antiretroviral therapy to HIV infected woman during pregnancy, delivery ,breast feeding & continuing the regimen to infants during breast feeding period will significantly prevent transmission from 30-45% to 2-5%.The aim of the study is to ascertain the changing trends with occurrence of HIV infection in children through the PPTCT programme (launched by Director General NACO on 14th September 2012) in prevention of transmission of HIV from HIV infected mother to child. 259 Antenatal Women registered from September 2012 to June 2013 at 105 ICTC centres in Krishna District were studied.All infants born to HIV infected mother were referred to Early Infant Diagnosis (EID) centres for HIV testing through HIV DNA PCR testing at 6 weeks, 6months, 12 months and final confirmatory test at 18 months. Out of 259 Antenatal Women , ARV Prophylaxis was given to 126, ART given to 69, ART PLUS to 15, single dose Nevirapine to10 , 2 were not eligible for treatment , treatment was not initiated for 35 and 2 have missed the treatment. In 2011April-12 March , out of 337 children tested for Dried Blood Spot ,18 were tested positive .In 2012 April-13 March , out of 253 children for Dried Blood spot ,6 were tested positive .Where as in April 2013 –2013 September out of 146 children tested ,5were detected as HIV positive . In 2013 October-2013 June , out of 267 children tested , 1 case was detected as HIV positive .PPTCT programme can be effective if well conducted , thus minimal infectivity rate can be achieved in infants born to HIV infected mother. Keywords: PPTCT, PMTCT, HIV
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