Evaluation of antibacterial and antifungal activity of macro algae associated microbes from the Northern and Southern coast of Kenya
AbstractMarine macro algae are known to be an excellent source of bioactive compounds which have a broad range of biological activities including antibacterial and antioxidant. The surfaces of marine eukaryotes provide a unique habitat for colonizing microorganisms which also produce bioactive compounds. The Kenyan Indian Ocean is a host of numerous seaweeds species. The present study embarked on isolation of microbes that live in association with the macro algae collected from three sites in the Northern (Mtwapa and Mkomani) and Southern coast (Kibuyuni) of Kenya during the Southeast monsoon season. Microbes were isolated from different species of the red, green and brown macro algae and evaluated for their antibacterial and antifungal activity, against three human pathogens namely; Gram positive Staphylococcus aureus (ATCC 25922), Gram negative Escherichia Coli (ATCC 25923) and fungi Candida albicans (ATCC 90028). The study obtained 1609 microbes and 187 isolates showed inhibition potential against the test organisms, with most isolates (91) showing good activity against Escherichia Coli followed by Candida albicans (78 isolates) and Staphylococcus aureus (49 isolates) respectively. From the results, it clearly depicts the potential of the macro algae associated microbes. This means that the marine microbes may be useful in the treatment of various infectious caused by different pathogens. Key words: Antimicrobial potential, Bioactive compounds, Test organisms, Seaweeds,
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